Risks for First Nonfatal Myocardial Infarction in Belgrade

Isidora Ratkov, Sandra Šipetić-Grujičić, Hristina Vlajinac, Jelena Marinković, Nataša Maksimović, Dragana Matanović, Zorana Vasiljević

Abstract


The aim of this study was to investigate which one among possible risk factors are independently related to first nonfatal myocardial infarction (MI) in Belgrade population. Case-control study was conducted in Belgrade during the period 2005–2006. Case group comprised 100 subjects 35–80 years old who were hospitalized because of first nonfatal MI at the coronary care unit in Urgent Center, Belgrade. Control group consisted of 100 persons chosen among patients treated during the same period at the Institute of Rheumatology, Institute for Gastroenterology, and Clinic for Orthopedics, Belgrade, Serbia. Cases and controls were individually matched by sex, age (±2 years) and place of residence (urban/rural communities of Belgrade). According to the multivariate analysis risk factors for MI occurrence were »good« socioeconomic conditions (OR=2.76), total alcohol consumption (OR=2.62) and consumption of brandy (OR=6.73), stressful life events taken together (OR=3.13) and stress because of close relative Ns death (OR=3.35), great financial problems (OR=31.64) and small financial problems (OR=8.47), hypertension (OR=2.39), MI among all relatives (OR=3.66), MI in father (OR=6.24), and low level of high density lipoprotein cholesterol (OR=152.41). Amateur sport activity in the past was negatively associated with MI development. The results obtained are mainly in accordance with other studies results and can be of help in development of strategy for coronary heart disease prevention in Serbia.

Keywords*


case-control study, myocardial infarction, risk factors, alcohol, stress, hypertension, HDL-cholesterol, physical activity, genetic

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